| Name | Size | DLs |
|---|
| Saeki Chizu Shiki Yumemihada - Dream Skincare (Japan) | 84.42 mb | 1561 |
| Safari Adventures - Africa | 9.51 mb | 1381 |
| Safari Adventures - Africa (Europe) (En,Fr,De,Es,It,Nl) [b] | 9.51 mb | 1397 |
| Safecracker - The Ultimate Puzzle Challenge! | 28.78 mb | 1515 |
| SaGa 2 - Hihou Densetsu - Goddess of Destiny (Japan) | 45.83 mb | 3186 |
| SaGa 3 - Jikuu no Hasha - Shadow or Light (Japan) | 49.72 mb | 3095 |
| Saga no Gabai Baachan DS (Japan) | 12.05 mb | 1380 |
| Saibanin Suiri Game - Yuuzai x Muzai (Japan) | 14.82 mb | 1571 |
| Saihai no Yukue (Japan) | 17.54 mb | 1488 |
| Saikin Koi Shiteru (Japan) | 189.70 mb | 1891 |
| Saikyou Toudai Shougi DS (Japan) | 4.28 mb | 1217 |
| Sailor Moon - La Luna Splende (Italy) | 11.62 mb | 1524 |
| Saitou Takashi no DS de Yomu - Sanshoku Ballpen Meisaku Juku (Japan) | 6.21 mb | 1123 |
| Saiyuuki Kinkaku Ginkaku no Inbou (Japan) | 7.03 mb | 1386 |
| Saka Tsuku DS - Touch and Direct | 63.11 mb | 1743 |
| Saka Tsuku DS - World Challenge 2010 (Japan) [b] | 55.31 mb | 1805 |
| Sakana to Asobou! - Aquazone DS - Kaisuigyo (Japan) | 9.00 mb | 1162 |
| Sakashou DS (Japan) | 29.37 mb | 1316 |
| Sakura Note - Ima ni Tsunagaru Mirai (Japan) | 32.89 mb | 1531 |
| Sakusaku Jinkou Kokyuu Care Training DS (Japan) | 6.67 mb | 1188 |
| Sallys Salon (USA) | 2.34 mb | 1040 |
| Salon Superstar | 14.64 mb | 1378 |
| Sam Power - Footballer (Europe) (En,Fr,De,Es,It,Nl,Sv,No,Da) | 9.07 mb | 1247 |
| Samantha Oups! - Le Jeu (France) | 13.54 mb | 1189 |
| Samantha Swift and the Hidden Roses of Athena | 16.89 mb | 1378 |
| San-X Character Channel - All-Star Daishuugou! (Japan) | 11.31 mb | 1289 |
| San-X Character Sagashi Land (Japan) | 16.99 mb | 1246 |
| San-X Land - Theme Park de Asobou! (Japan) | 10.11 mb | 1256 |
| Sands of Destruction | 178.78 mb | 2908 |
| Sangokushi DS 2 | 32.52 mb | 1965 |
| Sangokushi Taisen DS (Japan) | 100.09 mb | 2262 |
| Sangokushi Taisen Ten (Japan) | 149.04 mb | 2431 |
| Sankei Sports Kanshuu - Keiba Ryoku Nintei Shiken - Baken DS (Japan) | 11.33 mb | 1123 |
| Sankei Sports Kanshuu - Wi-Fi Baken Yosou Ryoku Training - Umania 2007 Nendo Ban (Japan) | 5.94 mb | 1116 |
| Sansuu Puzzle de Migaku - Gakken Otona no Shikou Sense (Japan) | 3.24 mb | 1225 |
| Santa Claus is Comin to Town (USA) | 13.37 mb | 1327 |
| Sarah - Keeper of the Unicorn | 4.01 mb | 1136 |
| Sarah - Keeper of the Unicorn (USA) (En,Es) [b] | 4.00 mb | 968 |
| Saru Saru DS (Japan) | 17.25 mb | 1318 |
| Satisfashion - Rock the Runway | 10.92 mb | 1300 |
| SBI Group Kanshuu - Hajimeyou! Shisan Unyou DS (Japan) | 5.45 mb | 1133 |
| SBK - Snowboard Kids | 21.57 mb | 2185 |
| Scene It Twilight | 145.13 mb | 1757 |
| Schatz der Delfine, Der (Europe) (En,Fr,De,Es,It) | 8.72 mb | 1123 |
| Science Papa | 5.00 mb | 1248 |
| Scooby-Doo! - First Frights | 61.82 mb | 3120 |
| Scooby-Doo! - Unmasked | 5.03 mb | 2375 |
| Scooby-Doo! - Whos Watching Who | 13.35 mb | 2349 |
| Scooby-Doo! and the Spooky Swamp | 25.21 mb | 2599 |
| Scrabble - Crossword Game (USA) | 20.36 mb | 1468 |
| Scrabble Interactive - 2007 Edition (Europe) (En,Fr) | 8.84 mb | 1219 |
| Scrabble Interactive - 2009 Edition (Europe) (En,Fr) | 20.32 mb | 1324 |
| Scribblenauts | 12.34 mb | 3125 |
| Scribblenauts Collection (USA) | 17.81 mb | 2632 |
| Scripps Spelling Bee (USA) (NDSi Enhanced) | 29.27 mb | 1263 |
| Scurge - Hive | 4.04 mb | 1786 |
| SD Gundam G Generation - Cross Drive (Japan) | 35.52 mb | 1965 |
| SD Gundam G Generation DS (Japan) | 7.18 mb | 1864 |
| SD Gundam Sangoku Den - Brave Battle Warriors - Shin Militia Taisen (Japan) [b] | 13.40 mb | 1776 |
| Sea Monsters - A Prehistoric Adventure | 3.97 mb | 1654 |
| Sea Park Tycoon | 8.80 mb | 1475 |
| Secret Egg Distribution 2011 (USA) (Wi-Fi Kiosk) (Save Data) | 97.56 kb | 668 |
| Secret Files - Tunguska | 47.58 mb | 1929 |
| Secret Files 2 - Puritas Cordis (Europe) (En,Fr,De,Es,It) | 56.04 mb | 1881 |
| Secret Flirts - Make Everyone Fall For You! (Europe) (En,Fr,De,Es,It,Nl) | 12.12 mb | 1298 |
| Secret Key Distribution 2009 (USA) (Wi-Fi Kiosk) (Save Data) | 204.66 kb | 660 |
| Secret Saturdays, The - Beasts of the 5th Sun | 14.03 mb | 1459 |
| Secret Story - Le Jeu Officiel de lEmission (France) [b] | 2.59 mb | 855 |
| Secrets of the Titanic 1912-2012 (Europe) (En,Fr) | 13.40 mb | 1240 |
| Sega Casino | 2.84 mb | 1796 |
| Sega Superstars Tennis | 40.61 mb | 3068 |
| Seitokai no Ichizon - DS Suru Seitokai (Japan) | 78.50 mb | 1516 |
| Sekai Fushigi Hakken! DS - Densetsu no Hitoshi-kun Ningyou o Sagase! (Japan) | 9.82 mb | 1241 |
| Sekai no Hate made ItteQ! - Chinjuu Hunter Imoto no Daibouken (Japan) | 21.84 mb | 1288 |
| Sekai no Shougi (Japan) | 17.32 mb | 1230 |
| Sekaishi DS (Japan) | 7.38 mb | 1214 |
| Sengoku Spirits - Gunshi Den (Japan) | 6.33 mb | 1201 |
| Sengoku Spirits - Moushou Den (Japan) | 6.53 mb | 1236 |
| Sengoku Spirits - Shukun Den (Japan) | 6.38 mb | 1189 |
| Sesame Street - Elmos Musical Monsterpiece (USA) (En,Es) | 90.85 mb | 1760 |
| Settlement Colossus (Europe) (En,Fr,De,Nl) | 10.15 mb | 1198 |
| Settlers, The | 17.01 mb | 1876 |
| Shaberu! DS Oryouri Navi | 44.49 mb | 1673 |
| Shaberu! DS Oryouri Navi - Marugoto Teikoku Hotel (Japan) | 47.34 mb | 1523 |
| Shakugan no Shana DS (Japan) | 31.55 mb | 1401 |
| Shamus Deep Sea Adventures | 4.77 mb | 1224 |
| Shanghai (Japan) | 3.23 mb | 1216 |
| Shaun the Sheep | 9.84 mb | 1870 |
| Shaun the Sheep - Off His Head (Europe) (En,Fr,De,Es,It) | 10.73 mb | 1412 |
| Shaun White Snowboarding | 11.25 mb | 1757 |
| Shawn Johnson Gymnastics (USA) (En,Fr,Es) | 10.48 mb | 1272 |
| Shaymin Distribution 2009 (Europe) (En,Fr,De,Es,It) (Wi-Fi Kiosk) (Save Data) | 216.19 kb | 690 |
| Shaymin-Regigigas Distribution 2009 (USA) (Wi-Fi Kiosk) (Save Data) | 204.67 kb | 670 |
| Shepherds Crossing 2 DS | 6.20 mb | 1390 |
| Sherlock Holmes - The Mystery of the Mummy | 56.33 mb | 2165 |
| Sherlock Holmes and the Mystery of Osborne House | 12.13 mb | 1792 |
| Shibou Nenshou Keikaku - Yasetore!! DS (Japan) | 14.30 mb | 1196 |
| Shichida Shiki Training - Unou Tanren Unotan DS - Shun Kan Shoubu! Handanryoku (Japan) | 5.91 mb | 1180 |
| Shikaku Kentei DS (Japan) | 23.39 mb | 1318 |
| Shikakui Atama o Maruku Suru. DS - Joushiki, Nanmon no Shou (Japan) | 2.67 mb | 1207 |
| Shikakui Atama o Maruku Suru. DS - Kanji no Shou (Japan) | 2.65 mb | 1052 |
| Shikakui Atama o Maruku Suru. DS - Keisan no Shou (Japan) | 2.65 mb | 1066 |
| Shin Hisui no Shizuku - Hiiro no Kakera 2 DS (Japan) | 378.27 mb | 2020 |
| Shin Lucky Star Moe Drill - Tabidachi (Japan) | 69.60 mb | 1469 |
| Shin Maru Goukaku - Shikaku Dasshu! IT Passport Shiken, Kihon Jouhou Gijutsusha Shiken, Ouyou Jouhou Gijutsusha Shiken (Japan) | 17.93 mb | 1411 |
| Shin Megami Tensei - Devil Survivor | 49.61 mb | 5548 |
| Shin Megami Tensei - Devil Survivor 2 | 203.68 mb | 6689 |
| Shin Megami Tensei - Strange Journey | 104.80 mb | 5901 |
| Shin Noukyou Iku (Japan) (NDSi Enhanced) | 70.93 mb | 1588 |
| Shin Sengoku Tenka Touitsu - Gunyuu-tachi no Souran (Japan) | 40.55 mb | 1589 |
| Shining Force Feather (Japan) | 105.19 mb | 2560 |
| Shining Stars - Super Starcade | 2.84 mb | 1412 |
| Shinreigari - Ghost Hound DS (Japan) | 159.66 mb | 1846 |
| Shinri Kenkyuuka Yuki Yu Kanshuu - Mainichi Kokorobics - DS Therapy (Japan) | 14.61 mb | 1170 |
| Shinseiki Evangelion - Ayanami Ikusei Keikaku DS with Asuka Hokan Keikaku (Japan) [b] | 170.94 mb | 2052 |
| Shiny Dialga-Palkia-Giratina Distribution 2013 | 102.00 kb | 739 |
| Shiny Dialga-Palkia-Giratina Distribution 2013 (Europe) (En,Fr,De,It) (Wi-Fi Kiosk) (Save Data) | 98.34 kb | 625 |
| Shion no Ou - The Flowers of Hard Blood (Japan) | 13.56 mb | 1541 |
| Shiseido Beauty Solution Kaihatsu Center Kanshuu - Project Beauty (Japan) | 9.27 mb | 1339 |
| Shoho kara Hajimeru - Otona no Eitango Renshuu (Japan) | 9.92 mb | 1392 |
| Shokugyou Taiken Adventure - 13-sai no Hello Work DS (Japan) | 97.93 mb | 1546 |
| Shonen Magazine Comics Special Pack (Japan) (DSvision) | 31.57 mb | 1413 |
| Shonen Sunday Comics Special Pack (Japan) (DSvision) | 49.49 mb | 1485 |
| Shorts (USA) (En,Fr) | 21.00 mb | 1328 |
| Shougi World Champion - Gekisashi DS (Japan) | 12.70 mb | 1250 |
| Shoukou Shindan Training DS (Japan) | 4.57 mb | 1109 |
| Shounen Kininden Tsumuji (Japan) | 77.64 mb | 1506 |
| Shounen Sunday & Shounen Magazine - White Comic (Japan) | 59.27 mb | 1667 |
| Showtime Championship Boxing | 7.99 mb | 1403 |
| Shrek - Forever After | 119.22 mb | 2802 |
| Shrek - Ogres & Dronkeys | 79.67 mb | 2184 |
| Shrek - Smash n Crash Racing | 35.35 mb | 2169 |
| Shrek - Super Slam | 12.82 mb | 2111 |
| Shrek the Third | 49.82 mb | 2343 |
| Shreks Carnival Craze - Party Games | 46.49 mb | 1876 |
| Shugo Chara! - 3-tsu no Tamago to Koisuru Joker (Japan) | 20.08 mb | 1341 |
| Shugo Chara! - Amu no Nijiiro Chara Change (Japan) | 42.26 mb | 1514 |
| Shugo Chara! - Nori Nori! CharanaRhythm (Japan) | 74.80 mb | 1626 |
| Shuwa no Mori (Japan) | 13.64 mb | 1332 |
| Sid Meiers Civilization Revolution | 20.64 mb | 2402 |
| Sideswiped | 9.55 mb | 1474 |
| Sideswiped (USA) [b] | 9.63 mb | 1113 |
| Sightseeing Puzzle - Echter Puzzlespass fuer Unterwegs (Europe) (En,Fr,De,Es,It) [b] | 3.41 mb | 1095 |
| Sigma Harmonics (Japan) | 106.69 mb | 1796 |
| Signal (Japan) | 216.62 mb | 1988 |
| Silke - Pixelines Lillesoester - Syng, Leg og Laer (Denmark) [b] | 32.01 mb | 1068 |
| Sillybandz DS (USA) (En,Fr,Es) | 2.53 mb | 1041 |
| Silverlicious (USA) | 6.36 mb | 1183 |
| SimAnimals | 26.44 mb | 1980 |
| SimAnimals - Africa | 56.41 mb | 1787 |
| SimAnimals (Korea) (En,Ko) [b] | 13.20 mb | 969 |
| SimCity - Creator | 9.99 mb | 2399 |
| SimCity - Creator (Korea) [b] | 5.50 mb | 945 |
| SimCity DS | 7.42 mb | 3113 |
| Simple DS Series Vol. 1 - The Mahjong (Japan) | 3.22 mb | 1391 |
| Simple DS Series Vol. 10 - The Dokodemo Kanji Quiz (Japan) | 3.45 mb | 1118 |
| Simple DS Series Vol. 11 - Mou Ichido Kayoeru - The Otona no Shougakkou (Japan) | 1.76 mb | 1007 |
| Simple DS Series Vol. 12 - The Party Unou Quiz (Japan) | 4.02 mb | 1193 |
| Simple DS Series Vol. 14 - The Jidousha Kyoushuujo DS (Japan) | 2.66 mb | 1080 |
| Simple DS Series Vol. 15 - The Kanshikikan 2 - Aratanaru Yattsu no Jiken o Touch Seyo | 18.28 mb | 1560 |
| Simple DS Series Vol. 16 - The Sagasou Fushigi na Konchuu no Mori (Japan) | 7.38 mb | 1291 |
| Simple DS Series Vol. 18 - The Soukou Kihei Gun Ground (Japan) | 3.86 mb | 1241 |
| Simple DS Series Vol. 19 - Yareba Dekiru! - The Micro Step Gijutsu de Oboeru Eitango (Japan) | 13.16 mb | 1285 |
| Simple DS Series Vol. 20 - The Senkan (Japan) | 10.11 mb | 1332 |
| Simple DS Series Vol. 21 - The Hohei - Butai de Shutsugeki! Senjou no Inu-tachi (Japan) | 17.21 mb | 1636 |
| Simple DS Series Vol. 22 - Age Age - The Zero-Yon Midnight (Japan) | 11.99 mb | 1343 |
| Simple DS Series Vol. 24 - The Sensha (Japan) | 5.51 mb | 1209 |
| Simple DS Series Vol. 25 - The Koushounin (Japan) | 13.59 mb | 1358 |
| Simple DS Series Vol. 26 - The Quiz 30,000 Mon (Japan) | 9.02 mb | 1299 |
| Simple DS Series Vol. 27 - The Misshitsu kara no Dasshutsu - The Suiri Bangai Hen (Japan) | 17.36 mb | 1377 |
| Simple DS Series Vol. 28 - The Illust Puzzle & Suuji Puzzle 2 (Japan) | 576.69 kb | 863 |
| Simple DS Series Vol. 29 - The Sports Daishuugou - Yakyuu, Tennis, Volleyball, Futsal, Golf (Japan) | 9.21 mb | 1303 |
| Simple DS Series Vol. 30 - The Table Game - Mahjong, Igo, Shougi, Card, Hanafuda, Reversi, Gomoku Narabe (Japan) | 2.03 mb | 1135 |
| Simple DS Series Vol. 31 - The Chou Dangan!! Custom Sensha (Japan) | 3.87 mb | 1231 |
| Simple DS Series Vol. 32 - The Zombie Crisis (Japan) | 11.30 mb | 1568 |
| Simple DS Series Vol. 33 - The Crossword & Kanji Puzzle (Japan) | 7.07 mb | 1254 |
| Simple DS Series Vol. 34 - The Haisha-san (Japan) | 15.13 mb | 1259 |
| Simple DS Series Vol. 35 - The Genshijin (Japan) | 5.32 mb | 1205 |
| Simple DS Series Vol. 36 - ALC de Mi ni Tsuku! TOEIC Test - Bunpou Tokkun Hen (Japan) | 5.65 mb | 1260 |
| Simple DS Series Vol. 37 - ALC de Mi ni Tsuku! TOEIC Test - Listening Kyouka Hen (Japan) | 69.77 mb | 1497 |
| Simple DS Series Vol. 38 - ALC de Manabu! TOEIC Test - Hajimete Hen (Japan) | 20.53 mb | 1283 |
| Simple DS Series Vol. 39 - The Shouboutai (Japan) | 7.73 mb | 1251 |
| Simple DS Series Vol. 40 - The Gekai (Japan) | 7.99 mb | 1241 |
| Simple DS Series Vol. 41 - The Bakudan Shorihan (Japan) | 17.93 mb | 1320 |
| Simple DS Series Vol. 42 - The Haioku Byoutou - Norowareta Byouin kara no Dasshutsu (Japan) | 30.11 mb | 1615 |
| Simple DS Series Vol. 43 - The Host Shiyouze! - DX Night King (Japan) | 14.66 mb | 1354 |
| Simple DS Series Vol. 44 - The Gal Mahjong (Japan) | 40.20 mb | 1678 |
| Simple DS Series Vol. 45 - The Misshitsu kara no Dasshutsu 2 (Japan) | 19.61 mb | 1449 |
| Simple DS Series Vol. 46 - The Hikyou Tankentai - Choujou Special Kyoui! Jinrui Mitou no Sekai Kakuchi ni Nazo no Mikakunin Seibutsu wa Sonzai Shita!! (Japan) | 10.11 mb | 1407 |
| Simple DS Series Vol. 47 - The Suiri - Shinshou 2009 (Japan) | 11.11 mb | 1362 |
| Simple DS Series Vol. 48 - The Saibanin - 1-tsu no Shinjitsu, 6-tsu no Kotae (Japan) | 18.72 mb | 1433 |
| Simple DS Series Vol. 5 - The Trump (Japan) | 2.37 mb | 1059 |
| Simple DS Series Vol. 8 - The Kanshikikan - Kinkyuu Shutsudou! Jiken Genba o Touch Seyo! (Japan) | 17.40 mb | 1507 |
| Simple DS Series Vol. 9 - Atama ga Yokunaru - The Me no Training (Japan) | 1.46 mb | 977 |
| Simpsons Game, The | 455.33 mb | 4838 |
| Sims 2, The | 52.18 mb | 4066 |
| Sims 2, The - Apartment Pets | 10.21 mb | 2398 |
| Sims 2, The - Castaway | 24.65 mb | 2797 |
| Sims 2, The - Pets | 8.37 mb | 2329 |
| Sims 3, The | 56.51 mb | 4584 |
| Six Flags Fun Park (USA) (En,Fr) | 28.63 mb | 1601 |
| Skate It | 27.60 mb | 1824 |
| Skate It (USA) (En,Fr,De,Es,It,Nl) [b] | 27.60 mb | 1672 |
| Slide Adventure - Mag Kid (Japan) | 19.67 mb | 1291 |
| Slingo Quest (USA) | 2.64 mb | 1272 |
| Sloane to MacHale no Nazo no Story (Japan) | 38.23 mb | 1593 |
| Sloane to MacHale no Nazo no Story 2 (Japan) | 44.14 mb | 1636 |
| Smart Boys Gameroom | 17.83 mb | 1385 |
| Smart Boys Gameroom 2 | 6.53 mb | 1234 |
| Smart Boys Toys Club | 14.89 mb | 1234 |
| Smart Boys Toys Club (USA) [b] | 5.43 mb | 1012 |
| Smart Boys Winter Wonderland (USA) | 6.88 mb | 1133 |
| Smart Girls Magical Book Club (USA) | 21.17 mb | 1203 |
| Smart Girls Party Game | 15.46 mb | 1452 |
| Smart Girls Party Game (USA) [b] | 6.09 mb | 997 |
| Smart Girls Playhouse | 17.70 mb | 1291 |
| Smart Girls Playhouse 2 | 6.77 mb | 1218 |
| Smart Girls Playhouse Party (USA) | 15.10 mb | 1223 |
| Smart Girls Winter Wonderland (USA) | 6.29 mb | 1172 |
| Smart Kids Gameclub (USA) | 7.42 mb | 1128 |
| Smart Kids Mega Game Mix (USA) | 7.24 mb | 1156 |
| Smart Kids Party Fun Pak (USA) | 7.74 mb | 1216 |
| SmileyWorld - Island Challenge | 2.84 mb | 1105 |
| Smurfs 2, The | 20.07 mb | 1909 |
| Smurfs Collection, The (Europe) (En,Fr,De,Es,It,Nl,Sv,No,Da) | 36.80 mb | 2005 |
| Smurfs, The | 18.96 mb | 1790 |
| SNK vs. Capcom - Card Fighters DS | 20.84 mb | 3061 |
| Snood 2 - On Vacation | 2.52 mb | 1124 |
| Snoopy DS - Snoopy to Nakama-tachi ni Ai ni Ikou! (Japan) | 20.53 mb | 1416 |
| Snoopy no Aiken DS - Shitte Okitai Inu no Koto, Inu no Nouryoku, Anata no Shitsuke (Japan) | 6.37 mb | 1209 |
| Snoopy to Issho ni DS Eigo Lesson (Japan) | 17.82 mb | 1246 |
| So Blonde - Back to the Island (Europe) (En,Fr,De,Es,It) | 38.84 mb | 1380 |
| Sofie - Josefines Lillesoester - Hoensefoetter og Guleroetter | 53.53 mb | 1268 |
| Sofie - Josefines Lillesoester - Syng, Lek og Laer | 21.74 mb | 1134 |
| Sokoban DS (Europe) (En,Fr,De,Es,It) | 1.22 mb | 1033 |
| Solatorobo - Red the Hunter | 52.81 mb | 4338 |
| Solitaire | 3.51 mb | 1383 |
| Solitaire Mahjong - Ancient China Adventure (Europe) (En,Fr,De,Es,It) | 5.42 mb | 1192 |
| Solitaire Overload | 6.55 mb | 1256 |
| Solitaire Overload Plus | 5.53 mb | 1329 |
| Soma Bringer (Japan) | 76.63 mb | 2642 |
| Sommelier DS (Japan) | 20.48 mb | 1295 |
| Sonic & Sega All-Stars Racing | 44.98 mb | 6695 |
| Sonic Chronicles - The Dark Brotherhood | 137.65 mb | 11446 |
| Sonic Classic Collection | 28.82 mb | 7790 |
| Sonic Colors | 47.22 mb | 9368 |
| Sonic Rush | 30.31 mb | 11390 |
| Sonic Rush Adventure | 28.79 mb | 9872 |
| Sonic Rush Adventure (Korea) [b] | 27.30 mb | 1412 |
| Sonny with a Chance | 10.68 mb | 1372 |
| Sonshi no Heihou DS (Japan) | 76.05 mb | 1536 |
| Sonyeojeok Yeonae Hyeongmyeong - Love Revo!! DS (Korea) [b] | 38.33 mb | 1159 |
| Sora no Otoshimono Forte - Dreamy Season (Japan) | 96.80 mb | 1757 |
| Sorcerers Apprentice, The | 38.18 mb | 1626 |
| Soreike! Anpanman - Baikinman no Daisakusen (Japan) | 8.02 mb | 1203 |
| Soroban DS (Japan) | 15.04 mb | 1198 |
| Soukoku no Kusabi - Hiiro no Kakera 3 DS (Japan) | 365.83 mb | 2157 |
| Soul Bubbles | 21.38 mb | 2047 |
| Soul Eater - Medusa no Inbou (Japan) | 23.46 mb | 1737 |
| Souseiki Gadget Robo (Japan) | 14.65 mb | 1375 |
| Space Bust-A-Move | 11.04 mb | 2061 |
| Space Camp | 11.58 mb | 1454 |
| Space Chimps | 24.71 mb | 1574 |
| Space Invaders Extreme | 23.85 mb | 3596 |
| Space Invaders Extreme 2 | 25.28 mb | 3901 |
| Space Invaders Revolution | 4.63 mb | 2738 |
| Spanish Buddy (Europe) (Fr,De,It) [b] | 38.22 mb | 1457 |
| Spanish for Everyone! (USA) | 15.57 mb | 1201 |
| Spectral Force - Genesis | 62.12 mb | 2219 |
| Spectral Force - Genesis (Korea) [b] | 28.27 mb | 1048 |
| Spectrobes | 26.19 mb | 2363 |
| Spectrobes - Beyond the Portals | 106.51 mb | 2599 |
| Speed Racer - The Videogame | 31.48 mb | 2530 |
| Spelling Challenges and More! | 52.86 mb | 1479 |
| Spider-Man - Battle for New York | 117.16 mb | 3741 |
| Spider-Man - Edge of Time | 34.94 mb | 3405 |
| Spider-Man - Friend or Foe | 126.28 mb | 3757 |
| Spider-Man - Shattered Dimensions | 30.89 mb | 4148 |
| Spider-Man - Web of Shadows | 32.86 mb | 3491 |
| Spider-Man - Web of Shadows (USA) (En,Fr) [b] | 25.44 mb | 1944 |
| Spider-Man 2 | 14.39 mb | 3195 |
| Spider-Man 3 | 97.30 mb | 4056 |
| Spiderwick Chronicles, The | 26.18 mb | 1838 |
| Spiegel Online - Die Wissenstrainer-Serie - Allgemeinwissen (Germany) | 2.09 mb | 858 |
| Spiegel Online - Die Wissenstrainer-Serie - Karriere Coach (Germany) | 2.06 mb | 809 |
| Spiegel Online - Die Wissenstrainer-Serie - Life Coach (Germany) | 2.07 mb | 809 |
| Spiegel Online - Die Wissenstrainer-Serie - Weltreise (Germany) | 2.03 mb | 944 |
| Spielend Mathe Lernen (Germany) | 7.59 mb | 885 |
| Spitfire Heroes - Tales of the Royal Air Force (USA) | 7.44 mb | 1241 |
| SpongeBob SquarePants - Creature from the Krusty Krab | 15.34 mb | 2950 |
| SpongeBob SquarePants - Planktons Robotic Revenge | 47.27 mb | 3558 |
| SpongeBob SquarePants - The Yellow Avenger | 13.37 mb | 2912 |
| SpongeBob SquarePants featuring Nicktoons - Globs of Doom | 10.46 mb | 2110 |
| SpongeBob vs the Big One - Beach Party Cook-Off | 36.75 mb | 2248 |
| SpongeBob Yori Daesodong (Korea) [b] | 19.86 mb | 1012 |
| SpongeBobgwa Chingudeul (Korea) [b] | 10.09 mb | 973 |
| SpongeBobs Atlantis SquarePantis | 10.88 mb | 2723 |
| SpongeBobs Boating Bash | 20.02 mb | 2068 |
| SpongeBobs Surf & Skate - Roadtrip | 35.53 mb | 2139 |
| SpongeBobs Truth or Square | 9.10 mb | 2368 |
| Spore Creatures | 18.07 mb | 2134 |
| Spore Creatures (Korea) [b] | 16.40 mb | 1008 |
| Spore Hero Arena | 13.72 mb | 1665 |
| Sports Collection | 12.56 mb | 1471 |
| Sprung - A Game Where Everyone Scores | 10.11 mb | 1479 |
| Spy Kids - All the Time in the World (USA) | 6.54 mb | 1459 |
| Spyro - Shadow Legacy | 34.01 mb | 2930 |
| Squeeballs Party | 12.95 mb | 1357 |
| Squeeballs Party (Europe) (En,Fr,De,Es,It) [b] | 13.10 mb | 1034 |
| Squinkies - Surprise Inside | 31.76 mb | 1413 |
| Squinkies 2 - Adventure Mall Surprize! (USA) (En,Fr) | 15.01 mb | 1247 |
| Squishy Tank | 9.12 mb | 1289 |
| Star Fox Command | 24.12 mb | 5373 |
| Star Trek - Tactical Assault | 5.70 mb | 2092 |
| Star Wars - Battlefront - Elite Squadron | 33.17 mb | 3339 |
| Star Wars - Episode III - Revenge of the Sith | 15.55 mb | 3315 |
| Star Wars - Lethal Alliance | 12.49 mb | 2942 |
| Star Wars - The Clone Wars - Jedi Alliance | 291.40 mb | 4000 |
| Star Wars - The Clone Wars - Republic Heroes | 77.97 mb | 3240 |
| Star Wars - The Force Unleashed | 35.72 mb | 4773 |
| Star Wars - The Force Unleashed (Korea) [b] | 35.13 mb | 1158 |
| Star Wars - The Force Unleashed II | 86.62 mb | 4157 |
| Steal Princess | 15.50 mb | 1804 |
| Steal Princess - Touzoku Koujo (Japan) [b] | 15.91 mb | 1354 |
| Steel Horizon | 17.70 mb | 1489 |
| Sternenschweif - Das Geheimnis im Zauberwald (Germany) | 14.18 mb | 1042 |
| Sternentaenzer - Das Geheimnisvolle Pferd (Europe) (En,De) | 7.77 mb | 1226 |
| Steve Soresi no Business Eikaiwa Pera Pera DS Training (Japan) | 25.24 mb | 1328 |
| Steve Soresi no Eikaiwa Pera Pera DS Training (Japan) | 20.54 mb | 1257 |
| Stitch Jam | 28.41 mb | 2030 |
| Story of Noahs Ark, The (USA) | 12.12 mb | 1326 |
| Stratego - Next Edition (Europe) (En,Fr,De,Es,Nl) | 9.39 mb | 1265 |
| Strawberry Shortcake - Strawberryland Games | 5.85 mb | 1331 |
| Strawberry Shortcake - The Four Seasons Cake | 7.79 mb | 1367 |
| Street Football (Europe) (En,Fr,De,Es,It) | 28.81 mb | 1468 |
| Strike Witches - Soukuu no Dengekisen - Shin Taichou Funtou Suru! (Japan) | 150.60 mb | 1963 |
| Strike Witches 2 - Iyasu, Naosu, Punipuni Suru (Japan) [b] | 68.32 mb | 1921 |
| Style Book - Cinnamoroll (Japan) | 6.77 mb | 1131 |
| Style Book - Fushigi Boshi no Futago Hime Gyu! (Japan) | 7.99 mb | 1153 |
| Style Book - Junior City (Japan) | 2.52 mb | 1025 |
| Style Lab - Fashion Design (USA) (En,Fr,Es) | 11.02 mb | 1178 |
| Style Lab - Jewelry Design | 16.21 mb | 1299 |
| Style Lab - Makeover (USA) (En,Fr,Es) (NDSi Enhanced) | 11.13 mb | 1136 |
| Style Savvy | 249.51 mb | 3146 |
| Subbuteo (Europe) (En,Fr,De,Es,It) | 5.07 mb | 1310 |
| Successfully Learning English | 19.99 mb | 1328 |
| Successfully Learning English - Year 2+3 (Europe) (En,Fr,De,Es,It,Tr) | 10.63 mb | 1116 |
| Successfully Learning English - Year 4+5 (Europe) (En,Fr,De,Es,It,Tr) | 11.14 mb | 1137 |
| Successfully Learning Mathematics - Year 2+3 (Europe) (En,Fr,De,Es,It,Tr) | 5.50 mb | 1071 |
| Successfully Learning Mathematics - Year 4+5 (Europe) (En,Fr,De,Es,It,Tr) | 4.18 mb | 1077 |
| Successfully Learning Mathematics (Europe) (En,Fr,De,Es,It,Tr) | 7.30 mb | 1089 |
| Sudoku Ball Detective | 3.82 mb | 1155 |
| Sudoku Ball Detective (Europe) (En,Fr,De,Es,It,Nl) [b] | 3.82 mb | 987 |
| Sudoku DS - Nikoli no Sudoku Ketteiban (Japan) | 2.87 mb | 1144 |
| Sudoku Gridmaster | 4.27 mb | 1398 |
| Sudoku Mania - Enhance Your Critical Thinking Skills! | 2.03 mb | 1112 |
| Sudokuro - Sudoku & Kakuro Games | 1.17 mb | 978 |
| Sueddeutsche Zeitung Wissen - Mehr Kreuzwortraetsel | 2.19 mb | 926 |
| Sueddeutsche Zeitung Wissen - Mehr Kreuzwortraetsel (Germany) [b] | 2.16 mb | 813 |
| Sugar Bunnies DS - Yume no Sweets Koubou (Japan) (Rev 1) | 16.20 mb | 1288 |
| Sugar Sugar Rune - Queen Shiken wa Dai-panic (Japan) | 9.21 mb | 1267 |
| Suikoden - Tierkreis | 571.60 mb | 4706 |
| Suisui Physical Assessment Training DS (Japan) [b] | 22.16 mb | 1334 |
| Suite Life of Zack & Cody, The - Circle of Spies | 8.45 mb | 1326 |
| Suite Life of Zack & Cody, The - Tipton Trouble (USA) (En,Fr) | 9.16 mb | 1432 |
| Suite PreCure - Melody Collection (Japan) | 30.92 mb | 1550 |
| Sukashikashipanman DS - Shokotan Koto Nakagawa Shoko Produce (Japan) | 43.54 mb | 1426 |
| Suki Desu Suzuki-kun!! - 4-nin no Suzuki-kun (Japan) | 30.94 mb | 1289 |
| Summon Night - Twin Age | 86.87 mb | 3179 |
| Summon Night (Japan) | 48.96 mb | 1917 |
| Summon Night 2 (Japan) | 64.25 mb | 1928 |
| Summon Night X - Tears Crown (Japan) | 145.52 mb | 2244 |
| Sunday x Magazine - Nettou! Dream Nine (Japan) | 51.79 mb | 1539 |
| Sunrise Anime Zuke - Boku no Joushiki, Kimi no Hijoushiki - Vol. 1 (Japan) | 104.61 mb | 1547 |
| Supa Robo Gakuen (Japan) | 49.21 mb | 1998 |
| Super Auto Salon - Custom Car Contest (Japan) | 12.02 mb | 1239 |
| Super Black Bass Fishing | 4.74 mb | 1406 |
| Super Card DS (World) (Unl) [b] | 45.47 kb | 659 |
| Super Card DS One SDHC | 46.97 kb | 697 |
| Super Card DS Two (World) (Unl) | 28.63 kb | 667 |
| Super Collapse! 3 (USA) | 6.41 mb | 1301 |
| Super Dodgeball Brawlers | 4.27 mb | 1649 |
| Super Fahrschule (Germany) | 3.80 mb | 887 |
| Super Fruit Fall | 2.87 mb | 1148 |
| Super Fun Chess | 1.61 mb | 1034 |
| Super Fun Chess (Europe) (En,De,Es,It) [b] | 1.59 mb | 997 |
| Super Fun Sudoku (Europe) (En,De,Es,It) [b] | 1.11 mb | 793 |
| Super Key | 29.42 kb | 737 |
| Super Mario 64 DS | 14.23 mb | 21699 |
| Super Monkey Ball - Touch & Roll | 25.10 mb | 4267 |
| Super Princess Peach | 7.79 mb | 7647 |
| Super Robot Taisen K (Japan) | 41.92 mb | 2786 |
| Super Robot Taisen L (Japan) | 77.61 mb | 3217 |
| Super Robot Taisen OG Saga - Endless Frontier | 96.31 mb | 3961 |
| Super Robot Taisen OG Saga - Masou Kishin - The Lord of Elemental (Japan) | 47.97 mb | 2600 |
| Super Robot Taisen W (Japan) | 39.59 mb | 3047 |
| Super Scribblenauts | 15.98 mb | 3287 |
| Super Speed Machines | 21.50 mb | 1557 |
| Super Star Kartz | 46.84 mb | 1857 |
| Superman Returns | 26.44 mb | 2215 |
| Supermodel Makeover by Lauren Luke (Europe) (En,Fr,De,It) | 13.20 mb | 1187 |
| Surfs Up | 15.16 mb | 1541 |
| Survivor | 16.78 mb | 1678 |
| Sushi Academy | 8.87 mb | 1430 |
| Sushi Go-Round (USA) (En,Fr,De,Es,It) (NDSi Enhanced) | 3.52 mb | 1277 |
| Suugaku Master DS (Japan) | 3.23 mb | 1079 |
| Suujin Taisen (Japan) | 10.83 mb | 1380 |
| Suzuki Super-Bikes II - Riding Challenge (USA) | 12.62 mb | 1528 |
| Suzumiya Haruhi no Chokuretsu (Japan) [b] | 87.36 mb | 1739 |
| Sweet 16 (Europe) (En,Fr,De,Es,It) [b] | 10.09 mb | 1176 |
