| Name | Size | DLs |
|---|
| S.S. Lucifer - Man Overboard! (Europe) | 134.00 kb | 303 |
| Samurai Shodown (USA) | 312.73 kb | 572 |
| Samurai Spirits (Japan) | 317.48 kb | 417 |
| Scratch Golf (Japan) | 151.33 kb | 291 |
| Scratch Golf (USA) | 151.42 kb | 399 |
| SD Gundam - Winner's History (Japan) | 240.96 kb | 466 |
| Sega Game Pack 4 in 1 (Europe) | 124.74 kb | 387 |
| Sega Game Pack 4 in 1 (Europe) (Beta) | 117.24 kb | 179 |
| Sensible Soccer (Europe) | 73.08 kb | 346 |
| Shadam Crusader - Harukanaru Oukoku (Japan) | 406.75 kb | 428 |
| Shanghai II (Japan) | 46.04 kb | 284 |
| Shanghai II (Japan) (Rev 1) | 46.10 kb | 298 |
| Shaq Fu (USA, Europe) | 282.21 kb | 375 |
| Shikinjou (Japan) | 70.15 kb | 352 |
| Shining Force Gaiden - Ensei, Jashin no Kuni e (Japan) | 316.97 kb | 704 |
| Shining Force Gaiden - Final Conflict (Japan) | 402.38 kb | 780 |
| Shining Force Gaiden II - Jashin no Kakusei (Japan) | 378.83 kb | 525 |
| Shining Force II - The Sword of Hajya (USA) | 376.86 kb | 943 |
| Shinobi (USA, Europe) | 181.85 kb | 1223 |
| Shinobi II - The Silent Fury (World) (Ja) | 170.37 kb | 1488 |
| Side Pocket (USA) | 103.59 kb | 404 |
| Simpsons, The - Bart vs. the Space Mutants (USA, Europe) | 148.52 kb | 494 |
| Simpsons, The - Bart vs. the World (World) | 168.17 kb | 582 |
| Skweek (Japan) | 53.57 kb | 359 |
| Slider (USA, Europe) | 54.88 kb | 387 |
| Smurfs Travel the World, The (Europe) (En,Fr,De,Es) | 148.11 kb | 656 |
| Smurfs, The (Europe) (En,Fr,De,Es) | 135.95 kb | 425 |
| Solitaire FunPak (USA) | 127.06 kb | 292 |
| Solitaire Poker (USA, Europe) | 66.34 kb | 294 |
| Sonic & Tails (Japan) (En) | 221.96 kb | 814 |
| Sonic & Tails (Japan) (En) (Sample) | 226.97 kb | 266 |
| Sonic & Tails 2 (Japan) | 281.95 kb | 732 |
| Sonic Blast (World) | 458.03 kb | 1956 |
| Sonic Chaos (USA, Europe) | 222.70 kb | 1511 |
| Sonic Drift (Japan) | 182.94 kb | 979 |
| Sonic Drift (Japan) (Sample) | 184.53 kb | 248 |
| Sonic Drift 2 (Japan, USA) | 293.99 kb | 1704 |
| Sonic Labyrinth (World) | 212.05 kb | 1157 |
| Sonic The Hedgehog - Triple Trouble (USA, Europe) | 282.65 kb | 1952 |
| Sonic The Hedgehog (Japan) | 155.23 kb | 707 |
| Sonic The Hedgehog (World) (Proto) | 145.50 kb | 366 |
| Sonic The Hedgehog (World) (Rev 1) | 155.26 kb | 1436 |
| Sonic The Hedgehog 2 (World) | 223.37 kb | 2228 |
| Sonic The Hedgehog Spinball (USA, Europe) | 230.06 kb | 903 |
| Soukoban (Japan) | 47.31 kb | 376 |
| Space Harrier (World) | 88.74 kb | 726 |
| Spider-Man - Return of the Sinister Six (USA, Europe) | 151.00 kb | 635 |
| Spider-Man - X-Men - Arcade's Revenge (USA) | 222.65 kb | 510 |
| Spider-Man vs. The Kingpin (USA, Europe) | 142.87 kb | 537 |
| Spirou (Europe) (Proto) | 294.64 kb | 348 |
| Sports Illustrated Championship Football & Baseball (USA, Europe) | 199.52 kb | 267 |
| Sports Trivia - Championship Edition (USA, Europe) | 214.86 kb | 274 |
| Sports Trivia (USA) | 102.89 kb | 269 |
| Star Trek - The Next Generation - The Advanced Holodeck Tutorial (USA) | 163.46 kb | 383 |
| Star Trek Generations - Beyond the Nexus (USA, Europe) | 147.88 kb | 380 |
| Star Wars (Europe) | 275.19 kb | 307 |
| Star Wars (USA) | 275.18 kb | 530 |
| Stargate (World) | 132.18 kb | 463 |
| Street Hero (USA) (Proto 1) | 171.98 kb | 313 |
| Street Hero (USA) (Proto 2) | 166.71 kb | 332 |
| Striker (Europe) (En,Fr,De,Es,It) | 245.29 kb | 553 |
| Super Battletank (USA) | 130.73 kb | 341 |
| Super Columns (Japan) | 62.63 kb | 324 |
| Super Columns (USA, Europe) | 61.05 kb | 495 |
| Super Golf (Japan) | 63.18 kb | 355 |
| Super Kick Off (Japan) | 99.77 kb | 331 |
| Super Momotarou Dentetsu III (Japan) | 386.81 kb | 485 |
| Super Monaco GP (Japan) | 63.94 kb | 333 |
| Super Monaco GP (USA, Europe) | 64.00 kb | 432 |
| Super Off Road (USA, Europe) | 61.68 kb | 437 |
| Super Return of the Jedi (USA, Europe) | 335.65 kb | 495 |
| Super Smash T.V. (World) | 88.18 kb | 501 |
| Super Space Invaders (USA, Europe) | 129.71 kb | 495 |
| Superman - The Man of Steel (Europe) | 90.02 kb | 488 |
| Superman - The Man of Steel (Europe) (Beta) | 90.00 kb | 181 |
| Surf Ninjas (USA) | 283.03 kb | 432 |
| Sylvan Tale (Japan) | 319.80 kb | 644 |
