| Name | Size | DLs |
|---|
| S.S. Lucifer - Man Overboard! (Europe) | 120.15 kb | 895 |
| Samurai Shodown (USA) | 275.82 kb | 1688 |
| Samurai Spirits (Japan) | 280.94 kb | 1150 |
| Scratch Golf (Japan) | 136.04 kb | 820 |
| Scratch Golf (USA) | 136.04 kb | 1245 |
| SD Gundam - Winners History (Japan) | 199.99 kb | 1166 |
| Sega Game Pack 4 in 1 (Europe) | 110.59 kb | 1175 |
| Sega Game Pack 4 in 1 (Europe) (Beta) | 103.62 kb | 606 |
| Sensible Soccer (Europe) | 66.09 kb | 911 |
| Shadam Crusader - Harukanaru Oukoku (Japan) | 281.37 kb | 1095 |
| Shanghai II (Japan) | 39.51 kb | 846 |
| Shanghai II (Japan) (Rev 1) | 39.52 kb | 801 |
| Shaq Fu (USA, Europe) | 257.38 kb | 1248 |
| Shikinjou (Japan) | 63.02 kb | 918 |
| Shining Force Gaiden - Ensei, Jashin no Kuni e (Japan) | 294.99 kb | 1468 |
| Shining Force Gaiden - Final Conflict (Japan) | 379.31 kb | 2895 |
| Shining Force Gaiden II - Jashin no Kakusei (Japan) | 357.14 kb | 1403 |
| Shining Force II - The Sword of Hajya (USA) | 355.39 kb | 2020 |
| Shinobi (USA, Europe) | 167.97 kb | 2475 |
| Shinobi II - The Silent Fury (World) (Ja) | 155.70 kb | 2543 |
| Side Pocket (USA) | 86.68 kb | 1097 |
| Simpsons, The - Bart vs. the Space Mutants (USA, Europe) | 134.03 kb | 1439 |
| Simpsons, The - Bart vs. the World (World) | 152.75 kb | 1600 |
| Skweek (Japan) | 45.92 kb | 942 |
| Slider (USA, Europe) | 47.53 kb | 1103 |
| Smurfs Travel the World, The (Europe) (En,Fr,De,Es) | 139.52 kb | 1439 |
| Smurfs, The (Europe) (En,Fr,De,Es) | 119.44 kb | 1183 |
| Solitaire FunPak (USA) | 118.41 kb | 940 |
| Solitaire Poker (USA, Europe) | 60.40 kb | 902 |
| Sonic & Tails (Japan) (En) | 194.46 kb | 1991 |
| Sonic & Tails (Japan) (En) (Sample) | 199.03 kb | 735 |
| Sonic & Tails 2 (Japan) | 248.64 kb | 1845 |
| Sonic Blast (World) | 374.11 kb | 5093 |
| Sonic Chaos (USA, Europe) | 195.68 kb | 4288 |
| Sonic Drift (Japan) | 143.28 kb | 3735 |
| Sonic Drift (Japan) (Sample) | 144.90 kb | 740 |
| Sonic Drift 2 (Japan, USA) | 256.07 kb | 4041 |
| Sonic Labyrinth (World) | 172.08 kb | 2643 |
| Sonic The Hedgehog - Triple Trouble (USA, Europe) | 249.26 kb | 5588 |
| Sonic The Hedgehog (Japan) | 139.75 kb | 1556 |
| Sonic The Hedgehog (World) (Proto) | 130.58 kb | 911 |
| Sonic The Hedgehog (World) (Rev 1) | 139.71 kb | 3537 |
| Sonic The Hedgehog 2 (World) | 191.40 kb | 4804 |
| Sonic The Hedgehog 2 (World) (Auto Demo) | 55.44 kb | 956 |
| Sonic The Hedgehog Spinball (USA, Europe) | 195.10 kb | 2214 |
| Soukoban (Japan) | 41.40 kb | 1343 |
| Space Harrier (World) | 80.63 kb | 1695 |
| Spider-Man - Return of the Sinister Six (USA, Europe) | 132.35 kb | 1565 |
| Spider-Man - X-Men - Arcades Revenge (USA) | 194.53 kb | 1555 |
| Spider-Man vs. The Kingpin (USA, Europe) | 133.23 kb | 1524 |
| Spirou (Europe) (Proto) | 230.51 kb | 797 |
| Sports Illustrated Championship Football & Baseball (USA, Europe) | 160.53 kb | 920 |
| Sports Trivia - Championship Edition (USA, Europe) | 201.35 kb | 862 |
| Sports Trivia (USA) | 98.48 kb | 938 |
| Star Trek - The Next Generation - The Advanced Holodeck Tutorial (USA) | 147.94 kb | 1120 |
| Star Trek Generations - Beyond the Nexus (USA, Europe) | 134.93 kb | 1423 |
| Star Wars (Europe) | 241.49 kb | 920 |
| Star Wars (USA) | 241.49 kb | 1612 |
| Stargate (World) | 120.69 kb | 1343 |
| Street Hero (USA) (Proto 1) | 145.36 kb | 739 |
| Street Hero (USA) (Proto 2) | 139.14 kb | 721 |
| Striker (Europe) (En,Fr,De,Es,It) | 203.52 kb | 956 |
| Super Battletank (USA) | 113.66 kb | 1070 |
| Super Columns (Japan) | 58.32 kb | 946 |
| Super Columns (USA, Europe) | 56.88 kb | 1449 |
| Super Golf (Japan) | 55.57 kb | 1080 |
| Super Golf (USA) | 55.59 kb | 990 |
| Super Kick Off (Japan) | 84.26 kb | 913 |
| Super Momotarou Dentetsu III (Japan) | 362.82 kb | 1110 |
| Super Monaco GP (Japan) | 56.22 kb | 911 |
| Super Monaco GP (USA, Europe) | 56.04 kb | 1303 |
| Super Off Road (USA, Europe) | 54.55 kb | 1210 |
| Super Return of the Jedi (USA, Europe) | 309.26 kb | 1625 |
| Super Smash T.V. (World) | 76.61 kb | 1356 |
| Super Space Invaders (USA, Europe) | 114.58 kb | 1386 |
| Superman - The Man of Steel (Europe) | 79.49 kb | 1255 |
| Superman - The Man of Steel (Europe) (Beta) | 79.45 kb | 742 |
| Surf Ninjas (USA) | 248.13 kb | 1208 |
| Sylvan Tale (Japan) | 290.65 kb | 1657 |
